MALLINCKRODT BAKER INC -- DIMETHYL SULFOXIDE, 4948  -- -
<pre>=====================  Product Identification  =====================

Product ID:DIMETHYL SULFOXIDE, 4948
MSDS Date:12/08/1996
FSC:NIIN:Submitter:N EN
Status Code:A
=== Responsible Party ===
Company Name:MALLINCKRODT BAKER INC
Address:222 RED SCHOOL LANE
City:PHILLIPSBURG
State:NJ
ZIP:08865
Country:US
Info Phone Num:800-582-2537
Emergency Phone Num:202-463-7616;800-424-9300
Resp. Party Other MSDS Num.:D7120
Chemtrec Ind/Phone:(800)424-9300
CAGE:70829
=== Contractor Identification ===
Company Name:MALLINCKRODT BAKER,  INC.
Address:222 RED SCHOOL LANE
Box:City:PHILLIPSBURG
State:NJ
ZIP:08865
Country:US
Phone:800-582-2537
CAGE:70829

=============  Composition/Information on Ingredients  =============

Ingred Name:DIMETHYL SULFOXIDE
CAS:67-68-5
RTECS #:PV6210000
Minumum % Wt:99.
Maxumum % Wt:100.

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:LD50: (ORAL,RAT) 14,500 MG/KG
Routes of Entry: Inhalation:YES  Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:ACUTE: INHAL: CAUSES IRRITATION TO
    RESPIRATORY TRACT. SYMPS MAY INCL COUGHING, SHORTNESS OF BREATH.
    MAY CAUSE ALLERGIC REACTION IN SENSITIVE INDIVIDUALS. INGEST:
    CAUSES IRRITATION TO GI TRACT. SYMPS M AY INCL NAUSEA, VOMITING &
    DIARRHEA. MAY CAUSE ABDOMINAL PAIN, DROWSINESS, CHILLS & CHEST
    PAINS. SKIN CONT: CAUSES IRRITATION TO SKIN. SYMPS INCL REDNESS,
    ITCHING, & PAIN. MAY CAUSE SCALING. READILY A BSORBED THROUGH SKIN.
    GARLIC-LIKE TASTE & ODOR MAY DEVELOP ON THE BREATH & SKIN.
    TRANSIENT DISTURBANCES OF COLOR VISION, PHOTOPHOBIA, HEADACHE,
    DIARRHEA, AND DERMATITIS ABSORPTION OF OTHER MORE (EFTS  OF
    OVEREXP)
Effects of Overexposure:HLTH HAZS: TOXIC MATERIALS. EYE CONT: CAUSES
    IRRITATION, REDNESS, AND PAIN. MAY CAUSE BLURRED VISION. CHRONIC
    EXPOSURE: ABSORPTION MAY AFFECT THE BLOOD. REPEATED SKIN
    APPLICATION MAY CAUSE SCALING DER MATITIS. REPEATED ORAL DOSES MAY
    EFFECT THE LIVER AND KIDNEYS.
Medical Cond Aggravated by Exposure:PERSONS W/PRE-EXISTING SKIN
    DISORDERS/EYE PROBLEMS OR IMPAIRED LIVER OR KIDNEY FUNC MAY BE MORE
    SUSCEPTIBLE TO EFTS OF SUBSTANCE. TOPICAL APPLIC ENHANCES DERMAL
    ABSORP OF MANY OTHER CHEMS,  (SUPDAT)

=======================  First Aid Measures  =======================

First Aid:INHAL: REMOVE TO FRESH AIR. IF NOT BREATHING, GIVE ARTIF
    RESP. IF BRTHG IS DFCLT, GIVE OXYG. GET MED ATTN. INGEST: INDUCE
    VOMITING IMMED AS DIRECTED BY MED PERSONNEL. NEVER GIVE ANYTHING BY
    MOUTH TO U NCON PERSON. GET MED ATTN. SKIN CONT: IMMED FLUSH
    W/PLENTY OF SOAP & WATER FOR AT LST 15 MINS WHILE REMOVING CONTAMD
    CLTHG & SHOES. GET MED ATTN. WASH CLTHG BEFORE REUSE. THOROUGHLY
    CLEAN SHOES BEFORE	REUSE. EYE CONT: IMMEDIATELY FLUSH W/PLENTY OF
    WATER FOR AT LST 15 MINS, LIFTING LOWER & UPPER EYELIDS OCCASNLY.
    GET MEDICAL ATTN IMMEDIATELY.

=====================  Fire Fighting Measures  =====================

Flash Point Method:CC
Flash Point:=88.9C, 192.F
Autoignition Temp:=215.C, 419.F
Lower Limits:2.6%
Upper Limits:42-63%
Extinguishing Media:DRY CHEMICAL, FOAM OR CARBON DIOXIDE.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
    EQUIPMENT . VAPORS CAN FLOW ALONG SURFACES TO DISTANT IGNTION
    SOURCE AND FLASH BACK.
Unusual Fire/Explosion Hazard:ABOVE FLASH POINT, VAPOR-AIR MIXTURES ARE
    EXPLOSIVE WITHIN FLAMMABLE LIMITS NOTED. SEALED CONTAINERS MAY
    RUPTURE WHEN HEATED. SENSITIVE TO STATIC DISCHARGE.

==================  Accidental Release Measures  ==================

Spill Release Procedures:VENTILATE AREA OF LEAK/SPILL. REMOVE ALL
    SOURCES OF IGNIT. WEAR APPROP PERSONAL PROT EQUIP AS SPECIFIED IN
    EXPOSURE CONTROLS/PERSONAL PROT SECTION. ISOLATE HAZ AREA. KEEP
    UNNEC & UNPROTECTED PERSONNEL  FROM ENTERING. CNTN & RECOVER LIQ
    WHEN POSS. USE NON-SPKG TOOLS & EQUIP. COLLECT LIQ IN APPROP
    CNTNR/ABSORB W/INERT MATL (E.G. VERMICULITE, DRY SAND, EARTH), &
    PLACE IN CHEM WASTE CNTNR. (SUPDAT)

======================	Handling and Storage  ======================

Handling and Storage Precautions:KEEP IN TIGHTLY CLOSED CONTAINER.
    STORE IN A COOL, DRY, VENTILATED AREA AWAY FROM SOURCES OF HEAT OR
    IGNITION. PROTECT AGAINST PHYSICAL DAMAGE.
Other Precautions:STORE SEPARATELY FROM REACTIVE OR COMBUSTIBLE
    MATERIALS, AND OUT OF DIRECT SUNLIGHT. CONTAINERS OF THIS MATERIAL
    MAY BE HAZARDOUS WHEN EMPTY SINCE THEY RETAIN PRODUCT RESIDUES
    (VAPORS, LIQUID); OBSERV E ALL WARNINGS AND PRECAUTIONS LISTED FOR
    THE PRODUCT.

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:FOR CNDTNS OF USE WHERE EXPOS TO SUBSTANCE IS
    APPARENT, CONSULT INDUSTRIAL HYGIENIST. FOR EMERGENCIES, OR
    INSTANCES WHERE EXPOSURE LEVELS ARE NOT KNOWN, USE NIOSH APPRVD
    FULL-FACEPIECE POSITIVE-PRESSU RE, AIR SUPPLIED RESP. WARNING:
    NIOSH APPRVD AIR-PURIFYING RESPS DO NOT PROTECT WORKERS IN
    OXYG-DEFICIENT ATMOSPHERES.
Ventilation:SYS OF LOC AND/OR GEN EXHST IS REC TO KEEP EMPLOYEE EXPOS
    AS LOW AS POSS. LOC EXHST VENT IS GEN PREF BECAUSE IT CAN CTL
    EMISSIONS OF (SUPDAT)
Protective Gloves:IMPERVIOUS GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYE WASH & DELUGE SHOWER MTG ANSI DESIGN
    CRITERIA . WEAR IMPERVIOUS PROT CLTHG, INCLUDING BOOTS, GLOVES, LAB
    COAT, APRON OR COVERALLS, AS APPROPRIATE, TO PREVENT SKIN CONTACT.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
AGGRAVATION OF PRE-EXISTING CNDNTS: INCL DRUGS & ALLERGENS OF MOD
    MOLECULAR WEIGHT. SPILL RELEASE PROC: DO NOT USE COMBUST MATLS,
    SUCH AS SAW DUST. DO NOT FLUSH TO SEWER! VENT: CONTAMINANT AT ITS
    SOUR CE, PVNTG DISPERSION OF IT INTO GEN WORK AREA. PLEASE REFER TO
    ACGIH DOCUMENT, INDUS VENT, MANUAL OF  (OTHER INFO)

==================  Physical/Chemical Properties  ==================

Boiling Pt:=188.9C, 372.F
Melt/Freeze Pt:=17.8C, 64.F
Vapor Pres:0.42 @ 20C(68F)
Vapor Density:2.7(AIR=1)
Spec Gravity:1.10
Solubility in Water:MISCIBLE
Appearance and Odor:CLEAR, COLORLESS LIQUID. HYGROSCOPIC. GARLIC-LIKE
    ODOR.
Percent Volatiles by Volume:100

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
STRONG OXIDANTS, ACYLHALIDES, ARYLHALIDES, BROMOBENZOYL ACETANILIDE,
    MAGNESIUM PERCHLORATE, PERCHLORIC ACID AND SODIUM HYDROXIDE.
Stability Condition to Avoid:STABLE UNDER ORDINARY CONDITIONS OF USE &
    STORAGE. HYGROSCOPIC. HEAT, FLAMES, IGNITION SOURCES AND
    INCOMPATIBLES.
Hazardous Decomposition Products:UPON HEATING >100C(212F), SULFUR
    DIOXIDE IS EVOLVED FROM SUBSTANCE. HAZARDOUS THERMO-OXIDATIVE
    DEGRADATION PRODUCTS FROM DMSO INCLUDE FORMALDEHYDE, METHYL
    MERCAPTAN AND SULFUR DIOXIDE.

===================  Toxicological Information	===================

Toxicological Information:ORALRAT LD50: 14,500 MG/KG. IRRIT DATA (STD
    DRAIZE, RABBIT): SKIN=500 MG/24 HOUR, MILD; EYE=500 MG24 HOUR,
    MILD. INVESTIGATED AS TUMORIGEN, MUTAGEN, REPRODUCTIVE EFFECTOR.
    CANCER LIST: INGRED: DIMETHY LSULFOXIDE (67-68-5) - NTP CARCIN -
    NO, ANTICIPATED - NO, IARC CATEGORY - NONE.

=====================  Ecological Information  =====================

Ecological:ENVIR FATE: WHEN RELEASE INTO SOIL, MATL IS NOT EXPECTED TO
    BIODEGRADE. WHEN RELEASED INTO SOIL, MATL MAY LEACH INTO
    GROUNDWATER. WHEN RELEASED INTO SOIL, MATL MAY EVAPORATE TO MOD
    EXTENT. WHEN RELEAS ED INTO WATER, MATL MAY EVAPORATE TO MOD
    EXTENT. THIS MATL IS NOT EXPECTED TO SIGNIFICANTLY BIOACCUMULATE.
    WHEN RELEASED INTO AIR, THIS MATL MAY BE MODERATELY DEGRADED BY RXN
    W/PHOTOCHEMICALLY PRDCED  HYDROXYL RADICALS. WHEN RELEASED INTO
    AIR, MATL MAY BE REMOVED FROM ATM TO MOD EXTENT BY WET DEPOSITION.
    ENVIR TOX: NO INFORMATION FOUND.

====================  Disposal Considerations  ====================

Waste Disposal Methods:WHATEVER CANNOT BE SAVED FOR RECOVERY/RECYCLING
    SHOULD BE MANAGED IN APPROP & APPRVD WASTE DISP FACITLITY.
    PROCESSING, USE/CONTAM OF PROD MAY CHANGE WASTE MANAGEMENT OPTIONS.
    STATE & LOC DISP REGS MAY  DIFFER FROM FED DISP REGS. DISPOSE OF
    CNTNR & UNUSED CONTENTS I/A/W FEDERAL, STATE & LOCAL REQUIREM ENTS.

===================  MSDS Transport Information  ===================

Transport Information:NOT REGULATED.

=====================  Regulatory Information  =====================

SARA Title III Information:FEDERAL, STATE & INTERNATIONAL REGS PART 1:
    INGRED: DIMETHYLSULFOXIDE (67-68-5): SARA 302: RQ: NO, TPQ: NO.
    SARA 313 - LIST: NO. CHEMICAL CATG: NO. STATE REGULATORY INFO:
    CONTAMINATED CLOTHING AND SHO ES. WASH CLOTHING BEFORE REUSE. IN
    ALL CASES, GET MEDICAL ATTENTION. PRODUCT USE: LABORATORY REAGENT.
    REVISION INFO: NEW 16 SECTION MSDS FORMAT, ALL SECTIONS HAVE BEEN
    REVISED.
Federal Regulatory Information:CHEM INVENTORY STATUS-PART 1. INGRED:
    DIMETHYLSULFOXIDE(67-68-5). TSCA-YES, EC-YES, JAPAN-YES,
    AUSTRALIA-YES. CHEM INVENTORY STATUS-PART 2. INGRED:
    DIMETHYLSULFOXIDE (67-68-5). --CANADA--KOREA-YES, DS L-YES,
    NDSL-NO, PHIL.-YES. FED, STATE &INTERNATION REGS - PART 2. INGRED:
    DIMETHYLSULFOXIDE (67-68-5). CERCLA-NO, -RCRA- 261.33-NO,
    -TSCA-8(D)-NO. CHEM WEAPONS CONVENTION: NO. TSCA 12(B):NO. CDTA: O,
     SARA 311/312: ACUTE: YES. CHRONIC: YES. FIRE: YES. PRESS: NO.
    REACTIVITY: NO. (PURE/LIQUID). AUSTRAL IAN HAZCHEM CODE: NO INFO
    FOUND. POISON SCHEDULE: S6. WHMIS: THIS MSDS HAS BEEN PREPARD
    (OTHER INFO)
State Regulatory Information:OTHER INFO: CAUSE IRRIT TO SKIN, EYES &
    RESP TRACT. COMBUST LIQ & VAP. LABEL PRECAUTIONS: AVOID BRTHG
    VAP/MIST. KEEP CNTNR CLSD. USE ONLY W/ADEQ VENT. AVOID CONT W/EYES,
    SKIN & CLTHG. WASH THOROUGHLY  AFTER HNDLG. KEEP AWAY FROM HEAT &
    FALME. LABEL FIRST AID: IF SWALLOWED, INDUCE VOMIT IMMED AS
    DIRECTED BY MED PERSONNEL. NEVER GIVE ANYTHING BY MOUTH TO UNCON
    PERSON. IF INHALED, REMOVE TO FRESH AIR.  IF NOT BRTHG, GIVE ARTF
    RESP. IF BRTHG IS DFCLT, GIVE OXYG. IN CASE OF CONT, IMMED FLUSH
    EYES/SKIN  W/PLENTY OF WATER FOR AT LST 15 MINS WHILE REMOVING
    (SARA TITLE III)

=======================  Other Information  =======================

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